Computational Biology PDF lecture Slides

Computational Biology

Instructor: Larry Ruzzo
Textbook: Richard Durbin, Sean R. Eddy, Anders Krogh and Graeme Mitchison, Biological Sequence Analysis  Probabilistic models of proteins and nucleic acids
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1:	Introduction; Bio Basics
	2:	Alignment; DNA Replication
	3:	BLAST; Scoring; DNA Sequencing
	4:	MLE & EM
		EM Example (.xls)
	5:	Motifs; Gene Regulation
	6:	HMMs
		HMM Example (.xls)
	7:	Gene Finding; Splicing
	8:	RNA Function & Structure
	9:	RNA Search & Discovery
	10:	ChIPseq & Summary